曲丽华，女，博士

研究方向：药物残留分析，中药有效成份分析

教育与工作经历：

2024年6月至今，yL23411永利集团，yl23411永利官网，副教授

2023年6月至今，河南农业大学，兽医学，博士后

2017年7月-2024年5月，yL23411永利集团，yl23411永利官网，讲师

2013年9月-2017年1月，清华大学，有机化学，博士

2010年9月-2013年7月，东北农业大学，应用化学，硕士

2006年9月-2010年7月，山东理工大学，化学工程与工艺，学士

科学研究：

主要从事药物残留检测、中药有效成份分析、国家标准制定等，主持山东省自然科学基金1项，农业农村部项目1项，横向课题5项。

近五年主持主要科研项目：

1. 纵向课题：山东省自然科学基金青年项目，ZR2024QC093，金雀异黄酮逆转tet(X5)介导替加环素耐药性的作用机制研究，2025.1.1-2027.12.31，主持。

2. 横向课题：喷雾助剂对植保无人机喷洒雾滴粒径及雾滴飘移的评估，2022.11至2024.10，主持

3. 纵向课题：农业农村部项目，14192009，农业行业标准制定和修订，2019.5.27-2019.12.31，主持。

代表成果：

(1) Ranran Hou, Fuli Zhu, Qianwen Wang, Guangying Chen, Rui Ding, Huijuan Qi, Mengting Wang, Yuting Liu, Zhihai Liu, Xiao Xiao, Wenrui Su, Lihua Qu. Quantification of sodium nitrophenolate residues in 14 animal-derived matrices via stable isotope correction UPLC-APCI-MS/MS following PAX SPE cleanup. Microchemical Journal, 2026, 224, 117828.

(2) Lihua Qu, Zhu Fuli, Qingrou Han, Chen Guangying, Liu Yuting, Li Yu, Lei Caiyun, Zhan Changpeng, Liu Yan, Du Xiang-Dang*, Hou Ranran*, Liu Zhihai*. Characterization of Mylabris cichorii, Epicauta aptera, and Huechys sanguinea by morphological examination, DNA barcoding identification and chromatography analysis methods. Microchemical Journal, 2025, 219: 115899.

(3) Zhihai Liu, Kang Li, Qianwen Wang, Chang Liu, Bei Wang, Ranran Hou, Yanru Diao, Jing Wang, Xiang-Dang Du*, Lihua Qu*. Isotopic internal standard correction for the determination of diludine residue in animal-derived matrix samples using enhanced matrix removal-lipid clean-up combined with ultra-performance liquid chromatography-tandem mass spectrometry. Microchemical Journal, 2023, 195:109395.

(4) 刘畅, 王蓓, 李康, 徐坤, 邱梅, 程雪晴, 郝智慧*, 曲丽华*.固相萃取-高效液相色谱法测定禽类可食性组织和蛋中氨丙啉残留. 现代食品科技, 2023, 39(6):1-10.

(5) Lihua Qu, Xiaoyu Qi, Li Zhao, Yu Zhang, Ronghua Zhuge, Zhihui Hao, Congmin Liu*, Development, validation, and use of a monitoring method for fipronil and its metabolites in chicken eggs by QuEChERS with online-SPE-LC-Q/Orbitrap analysis, Rapid communications in mass spectrometry, 2023, 37: e9518.

(6) Congmin Liu, Li Wang, Lixuan Pan, Wenqing Hou, Zhihui Hao*, Lihua Qu*. An automated streamlined method for the therapeutic drug monitoring of digoxin based on the online-solid-phase extraction liquid chromatography tandem high-resolution mass spectrometry. Rapid communications in mass spectrometry, 2021, 35(22): e9191.

(7) Lihua Qu, Lixuan Pan, Li Wang, Congmin Liu, Yanhong Tian, Zhihui Hao*. Development of an online solid-phase extraction-liquid chromatography-mass spectrometric analysis of oxcarbazepine and its active metabolite licarbazepine from plasma with a direct injection step, Journal of Chromatography B, 2019, 1125: 121710.

(8) Lihua Qu, Jing Qian, Ping Ma*, Zheng Yin*. Utilizing online-dual-SPE-LC with HRMS for the simultaneous quantification of amphotericin B, fluconazole, and fluorocytosine in human plasma and cerebrospinal fluid, Talanta, 2017, 165: 449-457.

(9) Lihua Qu, Yuanjie Fan, Wenjun Wang, Kai Ma*, Zheng Yin*. Development, validation and clinical application of an online-SPE-LC-HRMS/MS for simultaneous quantification of phenobarbital, phenytoin, carbamazepine, and its active metabolite carbamazepine 10,11-epoxide, Talanta, 2016, 158: 77-88.

(10) Lihua Qu, Wenjun Wang, Debin Zeng, Yaxin Lu, Zheng Yin*. Quantitative performance of online SPE-LC coupled to Q-Exactive for the analysis of sofosbuvir in human plasma, RSC Advances, 2015, 5: 98269-98277.

教学授课情况：承担《有机化学C》、《有机化学实验A》、《基础化学实验》等课程的本科教学任务。

邮箱：qlh@qau.edu.cn